Dr
Mathilde L. Reinle-Schmitt
(Excelsus Structural Solutions (Swiss) AG)
08/05/2018, 10:25
Tuesday, May 8th Morning (Day 2 Workshop)
Dr
James A. Kaduk
(North Central College - Poly Crystallography Inc. - Illinois Institute of Technology)
08/05/2018, 10:50
Tuesday, May 8th Morning (Day 2 Workshop)
As part of a continuing project, the room-temperature crystal structures of several commercial pharmaceutical APIs have been solved using synchrotron X-ray powder diffraction data (11-BM at APS), and optimized using density functional techniques. The molecules to be discussed include: 1. terazosin hydrochloride dihydrate (Hytrin), which was originally solved (but only approximately) using...
13.
Powder Diffraction File™ Coverage of Polymers used in Pharmaceutical and Biomedical Applications
Dr
Thomas Blanton
(International Centre for Diffraction Data)
08/05/2018, 11:15
Tuesday, May 8th Morning (Day 2 Workshop)
Polymers show a range of order from amorphous to semi-crystalline. Traditional organic analytical techniques, such as infrared spectroscopy (IR), differential scanning calorimetry (DSC), thermal gravimetric analysis (TGA), and nuclear magnetic resonance (NMR), are typically used for polymer analysis. Though X-ray diffraction (XRD) is not commonly used as the primary technique for polymer...
