Purpose To introduce JulianA, a novel algorithm for automatic treatment planning for proton therapy (PT). Its name combines our in-house treatment planning system, FIonA, with the Julia programming language.
Methods JulianA utilises a novel plan quality scoring system tailored to represent the clinical intent, encompassing prescribed dose levels and organ-at-risk (OAR) dose...
Purpose
Ocular malignancies are treated worldwide with proton therapy using a diverse set of accelerator delivery systems. Lateral margin usage remains consistent, despite variations in dose characteristics. This study quantifies the interchangeability of lateral margin and penumbra sharpness in ocular proton therapy, addressing a key treatment optimization factor.
Methods
In this study,...
Purpose: To improve the prediction of positron emission tomography (PET) activity for treatment verification of proton therapy, magnetic resonance (MR) and computed tomography (CT) images were combined to assign an elemental composition to voxels within the CT based on the tissues identified in the MR.
Methods: Clinical treatment plans were generated for six head and neck patients. The...
Purpose:
Rescanning, gating, and breath-hold are promising approaches for realising proton therapy treatments of moving targets, but decrease delivery efficiency, lengthening treatment delivery time. In PBS (Pencil Beam Scanning) proton therapy, two factors influence the treatment delivery time: the beam-on time and the dead time, which is the time required for energy-layer and spot-position...
Purpose: The Radixact Synchrony modality enables to correct in real-time for tumor motion during tomohelical treatments by adjusting jaws and/or MLC position (Schnarr, 2018). The Synchrony precision was already investigated but only with gamma index methodology, which prevents discrimination between dose and geometric errors. Thus, the aim of this study is to quantify the Synchrony...
Purpose: To assess the dosimetric gain on ipsilateral lung using robust optimization on the GTV (GTV-based) or ITV (ITV-based) instead of standard PTV optimization (PTV-based) for lung stereotactic body radiotherapy (SBRT) on the CyberKnife with Synchrony and X-sight spine tracking methods.
Methods: For on-line synchrony tracking, 15 lung SBRT were calculated with both GTV- and PTV-based...
Purpose
Radiotherapy with ultra-high dose rates (UHDR) or FLASH radiotherapy (RT), offers the potential of significant reduction in side effects for cancer patients, and associated improvement in quality of life. In the short term, new electron and proton beam facilities for FLASH are currently being installed or being upgraded to FLASH mode. The clinical application of such radiation...
