Science@FELs 2014

Session

Biology

16 Sept 2014, 09:00

WHGA/001 (Paul Scherrer Institute)

98. New opportunities with Free Electron Lasers to study membrane protein dynamics

Gebhard Schertler (Paul Scherrer Institut)

16/09/2014, 09:00

2. Radiation damage in serial femtosecond crystallography

Dr Karol Nass (Max Planck Institute for Medical Research)

16/09/2014, 09:35

Biology

Contributed Talk

Serial femtosecond crystallography (SFX) is an emerging technique for protein structure determination. SFX has been proposed as the method of choice for data collection of highly radiation sensitive systems such as nanocrystals in general and e.g. metalloproteins. Previous high resolution SFX measurements performed at the LCLS do not show any signs of radiation damage at a dose of <100 MGy....

29. Fixed Target 2D and 3D Protein Crystallography at XFELs

Dr Matthias Frank (Lawrence Livermore National Laboratory)

16/09/2014, 10:00

Biology

Contributed Talk

Over the last years, serial femtosecond nanoscrystallography (SFX) has been demonstrated successfully in a number of experiments at LCLS and SACLA. Most SFX appllications to date have used three-dimensional (3D) nano- or microcrystals and have utilized a liquid jet based sampe introduction approach. That approach typically requires large amounts of sample and is not conducive to measuring...

35. Macromolecular Crystallography at XFELs and LCLS: Current Status, Limitations and Future Plans

Sebastien Boutet (Linac Coherent Light Source)

16/09/2014, 10:25

Biology

Contributed Talk

One of the early success stories of XFELs is the technique of Serial Femtosecond Crystallography (SFX), where crystals are illuminated by the x-ray pulses one at a time and the biomolecular structure is deduced from integrating all these measurements. After a few years of development, the technique has reached some level of maturity. In this talk I will quickly review the state of...