Structural Biology enabled by XFELs and Cryo-EM

25 Jun 2019, 09:00 → 27 Jun 2019, 15:30 Europe/Zurich

WHGA 001 Auditorium (PSI WEST)

Gebhard Schertler (ETH Zurich/PSI), Michael Hennig (leadXpro AG)

--- Program available for download on the bottom of this page --

With the first encouraging SwissFEL experiments in structural biology delivering static and time-resolved information on compound binding it is time to discuss the recent developments and shape the future directions.

The areas to be covered by the talks are focused on the application of Serial Crystallography done at XFELs. Furthermore, recent developments on Cryo-EM as complementing method for bio-structure research will be captured. All lectures and discussions aim to answer the question: What are the benefits for drug discovery?

The contributions are structured around three sessions:

• Biostructural research at FELs
• Methods, Instrumentation and analysis tools enabling research at FELs
• Recent Developments in Cryo-Electron Microscopy

The symposium is co-organized and co-located with the BIO Division, the Photon Science Division of PSI and leadXpro AG.

Registration is closed. Limited number of single-day tickets for CHF 200/day are still available on request. Please send an email to: dd-swissfel@leadxpro.com

 

 

 

Directions to_PSI_E.pdf

Scientific Programm_DD@SwissFEL_final_REV4.pdf

Tuesday 25 June

09:00 → 10:30 Registration

10:30 → 10:45 Opening/Welcome Remarks

10:45 → 12:00 Session 1 - Structures and Functions at FELS

Convener: Michael Hennig

12:00 → 13:30 Lunch (Park InnovAARE Building PSI West)

13:30 → 14:45 Session 1 - Structures and Functions at FELS

Convener: Herbert Nar (Boehringer Ingelheim Pharma GmbH & Co.KG)

14:45 → 15:15 Coffee break

15:15 → 17:00 Session 1 - Structures and Function at FELS

Convener: Matthias Frech (Merck KGaA)

Wednesday 26 June

09:00 → 10:45 Session 2 - Drug Discovery with EM & X-ray

Convener: Sandra Jacob-Cowan

10:45 → 11:15 Coffee break

11:15 → 12:15 Session 2- Structure based Drug Discovery enabled by X-ray Crystallography on GPCR's

Convener: Roger Benoit (PSI)

12:15 → 13:45 Lunch: (Park InnovAARE Building PSI West)

13:45 → 15:30 Session 2 - Electron Diffraction

Convener: Michel Steinmetz

15:30 → 17:30 Visit to SwissFEL and SLS (Optional)

17:30 → 18:30 Special Talk: Richard Neutze (OASE Canteen)

19:00 → 20:30 Dinner: OASE Canteen (PSI East)

Thursday 27 June

09:00 → 10:45 Session 3 - Method & Instrumentation Developments

Convener: Rafael Abela

10:45 → 11:15 Coffee break

11:15 → 12:45 Session 3 - Method & Instrumentation Developments

Convener: Oliver Bunk

12:45 → 13:00 Closing remarks