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Ms Anna Sampanai (ASG Superconductors Spa and Department of Mathematics, University of Genoa, Genoa, Italy)04/11/2026, 15:30poster only
Objective
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The upright position of patients is related to significant changes of geometry and spatial arrangement of abdominal organs relative to the conventional supine position. As respiration acts on this altered anatomy, posture and breathing jointly determine the resulting abdominal motion. So far, this posture-breathing interaction which is relevant for upright RT is insufficiently... -
Wouter van Weerelt (RaySearch Laboratories & KTH Royal University of Technology)04/11/2026, 15:50poster only
Objectives:
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Beam delivery time (BDT) is an important consideration in particle arc therapy, particularly for carbon-ion arcs delivered using synchrotrons. Energy layer filtration can reduce BDT, but the current MU-based filtration may not optimally balance delivery efficiency and treatment quality. This study investigates alternative energy layer filtration strategies for upright... -
Guangsheng Li (GSI Helmholtzzentrum für Schwerionenforschung GmbH)04/11/2026, 16:10poster only
Objective: To quantify inter-fractional tumor variation in upright lung cancer radiotherapy and compare fraction-level and accumulated target coverage and normal-tissue sparing across five ITV-based planning strategies.
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Methods: Eight patients with lung cancer underwent upright planning CT and serial daily in-room CT. Following rigid alignment, target contours were propagated to daily CTs by... -
Zixin He (GSI Helmholtzzentrum für Schwerionenforschung GmbH)04/11/2026, 16:30poster only
Objective: Semi-dynamic arc for carbon ion radiotherapy currently uses coplanar arcs. In regions of high organ-at-risk (OAR) density, large portions of coplanar arcs may have occlusions that prevent meaningful delivery to the target. A non-coplanar arc that makes full use of the motion range afforded by upright positioning solutions may overcome this problem by finding a treatment path within...
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María Plana Herranz (CNAO)04/11/2026, 16:50poster only
Objective
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Upright particle therapy systems introduce new beam angle freedom, but also new challenges: limited inter-fractional imaging, sensitivity to anatomical changes, and the need for robust panning strategies adapted to this novel setup. Head and neck treatments are particularly demanding, as anatomical variations during the treatment course frequently led to plan adaptation,... -
Chrysa Rousi (Faculty of Nuclear Sciences and Physical Engineering, Czech Technical University in Prague, Prague, Czech Republic)04/11/2026, 17:10poster only
Purpose/Objectives
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The transition from recumbent radiotherapy (RT) to upright patient positioning introduces opportunities to reduce costs of RT facilities, enhance patient’s comfort, increase workflow efficiency, and potentially improve dosimetric outcomes [1] . While studies have examined the feasibility and design of upright systems, regular quality assurance (QA) and patient specific... -
Leonna Aranda (OncoRay - National Center for Radiation Research in Oncology)05/11/2026, 15:30poster only
Authors
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L. Aranda 1,2, D.F. Redaelli 3, T. Underwood 3,4, A. Hoffmann 1,2,5
Affiliations
1 - OncoRay, National Center for Radiation Research in Oncology, Dresden, 2 - Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, 3 - Research Department, Leo Cancer Care Ltd, 4 - Department of Medical Physics and Biomedical Engineering, University College London, 5 - Dresden University of Technology... -
Courtney Ford05/11/2026, 15:42poster only
The focus of this project is on the design of a new, dedicated upright MR
scanner for real-time imaging of patients during proton therapy treatment.Historically, MR imaging and proton therapy (PT) were done with patients
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in a recumbent position. Recently, the concept of performing PT in an upright position has gained interest in the PT community.[1, 2] Although the P3 in-beam MR scanner... -
Pit Arend (DKFZ, KIT)05/11/2026, 15:55poster only
Objective While the first clinical upright radiotherapy systems have been installed, their availability remains limited, and further research is required to explore potential benefits and limitations of this technique. This work presents the development of a custom research platform for upright radiotherapy, including both a rotation platform and a dedicated 3D Slicer extension. The...
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88. Methods and Evidence in Economic Evaluations of Modern Radiotherapy: A Systematic Mapping ReviewMr Fabio Veneruso (Centre Léon Bérard, CNRS, Université Lumière Lyon 2, Université Jean Monnet Saint-Étienne, emlyon business school, GATE, Lyon, France)05/11/2026, 16:08poster only
Objective
Economic evidence on modern radiotherapy has not kept pace with its technological development and remains heterogeneous in design, costing method and treatment of uncertainty. This systematic mapping review catalogues the peer-reviewed economic evaluations of modern radiotherapy, classifies their methodological choices and identifies decision-relevant gaps. It informs the...
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Daniel Richter (ETH Zurich)05/11/2026, 16:20poster only
Objectives: Upright radiotherapy offers potential therapeutic and financial advantages, yet posture-dependent differences in intrafractional respiratory motion remain poorly understood. Characterising these variations is essential for safe upright treatment planning and dose delivery[1]. We hypothesised that posture significantly alters breathing-induced motion, which can be quantified...
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Vasily Sorokin (University of Oxford)05/11/2026, 16:33poster only
Objective: Heightened interest in alpha-emitting radiopharmaceutical therapies has created a need for methods capable of resolving their highly heterogeneous activity and dose distributions at microscopic scales. Because alpha particles travel less than approximately 100 μm in tissue, macroscopic activity and mean-dose estimates may not represent local cellular exposure. We aim to develop a...
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Alhassan Aliyu Saad (Jagiellonian University, Krakow)05/11/2026, 16:45poster only
Objective:
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Hadron therapy, particularly carbon-ion therapy, delivers a sharp, highly localized dose via the Bragg peak, however, this same sharpness makes treatment outcomes sensitive to range uncertainties arising from anatomical variation [6]. Ion beams interaction in tissue involves both electromagnetic processes, responsible for energy deposition, and nuclear interactions that lead to the... -
Nicole Caballero-Canchanya (Loughborough University)05/11/2026, 16:58poster only
Objective
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Upright radiotherapy is emerging as an alternative to conventional supine delivery for head and neck (HN) cancer treatment, but immobilisation systems, principally custom-moulded thermoplastic masks, were designed and validated exclusively for supine positioning. The objective of this narrative review was to synthesise evidence on patient comfort during immobilisation and to apply...
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