The 2nd UPLIFT School for “Artificial Intelligence in Radiotherapy”

Session

Poster dissusion

4 Nov 2026, 16:00

Congressi Stefano Franscini (CSF)

87. Development of a 4D MRI Framework for Characterising Abdominal Motion in Supine and Upright Positions

Ms Anna Sampanai (ASG Superconductors Spa and Department of Mathematics, University of Genoa, Genoa, Italy)

04/11/2026, 16:00

poster only

Objective
The upright position of patients is related to significant changes of geometry and spatial arrangement of abdominal organs relative to the conventional supine position. As respiration acts on this altered anatomy, posture and breathing jointly determine the resulting abdominal motion. So far, this posture-breathing interaction which is relevant for upright RT is insufficiently...

76. Energy Layer Filtration for Upright Static Carbon Arcs

Wouter van Weerelt (RaySearch Laboratories & KTH Royal University of Technology)

04/11/2026, 16:15

poster only

Objectives:
Beam delivery time (BDT) is an important consideration in particle arc therapy, particularly for carbon-ion arcs delivered using synchrotrons. Energy layer filtration can reduce BDT, but the current MU-based filtration may not optimally balance delivery efficiency and treatment quality. This study investigates alternative energy layer filtration strategies for upright...

94. Dosimetric trade-offs between ITV expansion and robust optimization for inter-fractional anatomical variation in upright carbon-ion radiotherapy for lung cancer

Guangsheng Li (GSI Helmholtzzentrum für Schwerionenforschung GmbH)

04/11/2026, 16:30

poster only

Objective: To quantify inter-fractional tumor variation in upright lung cancer radiotherapy and compare fraction-level and accumulated target coverage and normal-tissue sparing across five ITV-based planning strategies.
Methods: Eight patients with lung cancer underwent upright planning CT and serial daily in-room CT. Following rigid alignment, target contours were propagated to daily CTs by...

92. Non-coplanar arc radiotherapy trajectory planning in Blender

Zixin He (GSI Helmholtzzentrum für Schwerionenforschung GmbH)

04/11/2026, 16:45

poster only

Objective: Semi-dynamic arc for carbon ion radiotherapy currently uses coplanar arcs. In regions of high organ-at-risk (OAR) density, large portions of coplanar arcs may have occlusions that prevent meaningful delivery to the target. A non-coplanar arc that makes full use of the motion range afforded by upright positioning solutions may overcome this problem by finding a treatment path within...

78. Shoot-Through Beams for Robust Head and Neck Proton Therapy in Upright Particle Therapy Systems

María Plana Herranz (CNAO)

04/11/2026, 17:00

poster only

Objective
Upright particle therapy systems introduce new beam angle freedom, but also new challenges: limited inter-fractional imaging, sensitivity to anatomical changes, and the need for robust panning strategies adapted to this novel setup. Head and neck treatments are particularly demanding, as anatomical variations during the treatment course frequently led to plan adaptation,...

72. Considerations for the quality assurance of upright photon and proton radiotherapy

Chrysa Rousi (Faculty of Nuclear Sciences and Physical Engineering, Czech Technical University in Prague, Prague, Czech Republic)

04/11/2026, 17:15

poster only

Purpose/Objectives
The transition from recumbent radiotherapy (RT) to upright patient positioning introduces opportunities to reduce costs of RT facilities, enhance patient’s comfort, increase workflow efficiency, and potentially improve dosimetric outcomes [1] . While studies have examined the feasibility and design of upright systems, regular quality assurance (QA) and patient specific...

97. Probabilistic clinical target model: combining anatomy-constrained primary tumor spread with lymphatic progression

Kristjan Anderle (Cosylab d.d., Ljubljana, Slovenia), Robert Jeraj (Faculty of Mathematics and Physics, University of Ljubljana, Slovenia), Ruoxu Xia (Cosylab d.d., Ljubljana, Slovenia;)

04/11/2026, 17:30

Purpose
The clinical target volume (CTV) is a weak link in the radiotherapy chain. In head and neck cancer it has two parts, and both are drawn as binary contours. The primary CTV is a margin expansion of the GTV, edited at anatomical barriers. The elective nodal CTV includes or leaves out whole lymph node levels. Yet the risk of microscopic disease varies continuously across voxels and...

98. Impact of higher multileaf collimator speed on plan quality for Upright vs supine photon radiotherapy

Björn Messing (RaySearch Laboratories, Sweden), Erik Engwall (RaySearch Laboratories, Sweden), Gregoire Vincent (Centre de Lutte contre le cancer Léon Bérard (CLB), France), Nkuebe Clément Moleko (Centre de Lutte contre le cancer Léon Bérard (CLB), France), Rasmus Bokrantz (RaySearch Laboratories, Sweden)

04/11/2026, 17:45

Objective
Upright linacs are expected to reach multileaf collimator (MLC) speeds of up to 10 cm/s. This study investigates how higher MLC speeds affect plan quality in upright versus supine plans.
Method
Volumetric modulated arc therapy plans for three lung and three prostate cancer patients were generated in RayStation v2025. Each patient had plans at MLC speeds of 2.5, 5, and 10 cm/s,...

81. ANTHROPOMETRIC PATIENT MODELLING AS A DESIGN BASIS FOR AN UPRIGHT PATIENT POSITIONING SYSTEM IN PAEDIATRIC MR-GUIDED PROTON THERAPY

Leonna Aranda (OncoRay - National Center for Radiation Research in Oncology)

05/11/2026, 16:00

poster only

Authors
L. Aranda 1,2, D.F. Redaelli 3, T. Underwood 3,4, A. Hoffmann 1,2,5
Affiliations
1 - OncoRay, National Center for Radiation Research in Oncology, Dresden, 2 - Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, 3 - Research Department, Leo Cancer Care Ltd, 4 - Department of Medical Physics and Biomedical Engineering, University College London, 5 - Dresden University of Technology...

89. Design of an Isocentric MRI-Guided Upright Particle Therapy System

Courtney Ford

05/11/2026, 16:15

poster only

The focus of this project is on the design of a new, dedicated upright MR
scanner for real-time imaging of patients during proton therapy treatment.

Historically, MR imaging and proton therapy (PT) were done with patients
in a recumbent position. Recently, the concept of performing PT in an upright position has gained interest in the PT community.[1, 2] Although the P3 in-beam MR scanner...

83. A rotation platform for upright radiotherapy research with anthropomorphic phantoms on standard linear accelerators and fixed-beam particle therapy systems

Pit Arend (DKFZ, KIT)

05/11/2026, 16:30

poster only

Objective While the first clinical upright radiotherapy systems have been installed, their availability remains limited, and further research is required to explore potential benefits and limitations of this technique. This work presents the development of a custom research platform for upright radiotherapy, including both a rotation platform and a dedicated 3D Slicer extension. The...

88. Methods and Evidence in Economic Evaluations of Modern Radiotherapy: A Systematic Mapping Review

Mr Fabio Veneruso (Centre Léon Bérard, CNRS, Université Lumière Lyon 2, Université Jean Monnet Saint-Étienne, emlyon business school, GATE, Lyon, France)

05/11/2026, 16:45

poster only

Objective

Economic evidence on modern radiotherapy has not kept pace with its technological development and remains heterogeneous in design, costing method and treatment of uncertainty. This systematic mapping review catalogues the peer-reviewed economic evaluations of modern radiotherapy, classifies their methodological choices and identifies decision-relevant gaps. It informs the...

80. Quantifying Posture-Dependent Respiratory Motion for Upright Radiotherapy Using AI-Tracked Cine MRI

Daniel Richter (ETH Zurich)

05/11/2026, 17:00

poster only

Objectives: Upright radiotherapy offers potential therapeutic and financial advantages, yet posture-dependent differences in intrafractional respiratory motion remain poorly understood. Characterising these variations is essential for safe upright treatment planning and dose delivery[1]. We hypothesised that posture significantly alters breathing-induced motion, which can be quantified...

82. Quantitative Timepix4 Imaging of Heterogeneous Alpha-Emitting Radiopharmaceutical Distributions in Tissue Sections

Vasily Sorokin (University of Oxford)

05/11/2026, 17:15

poster only

Objective: Heightened interest in alpha-emitting radiopharmaceutical therapies has created a need for methods capable of resolving their highly heterogeneous activity and dose distributions at microscopic scales. Because alpha particles travel less than approximately 100 μm in tissue, macroscopic activity and mean-dose estimates may not represent local cellular exposure. We aim to develop a...

96. Towards a Feasibility Study of Range Verification in Radioactive Carbon-Ion Beam Therapy using J-PET Scanner

Alhassan Aliyu Saad (Jagiellonian University, Krakow)

05/11/2026, 17:30

poster only

Objective:
Hadron therapy, particularly carbon-ion therapy, delivers a sharp, highly localized dose via the Bragg peak, however, this same sharpness makes treatment outcomes sensitive to range uncertainties arising from anatomical variation [6]. Ion beams interaction in tissue involves both electromagnetic processes, responsible for energy deposition, and nuclear interactions that lead to the...

95. Designing for Comfort: A Usability Engineering Gap in Upright Head and Neck Radiotherapy Immobilisation

Nicole Caballero-Canchanya (Loughborough University)

05/11/2026, 17:45

poster only

Objective
Upright radiotherapy is emerging as an alternative to conventional supine delivery for head and neck (HN) cancer treatment, but immobilisation systems, principally custom-moulded thermoplastic masks, were designed and validated exclusively for supine positioning. The objective of this narrative review was to synthesise evidence on patient comfort during immobilisation and to apply...