4D Workshop 2023

Session

Apéro / Facility Tour / Poster Session

Sep 9, 2023, 4:30 PM

WHGA/001 (PSI)

39. 3D-printed materials for end-to-end test phantoms in particle therapy

Jacob Brunner

9/9/23, 4:30 PM

37. 4D MRI and motion management in particle therapy

Anestis Nakas

9/9/23, 4:30 PM

22. A national phase II study of proton therapy for hepatocellular carcinoma

Britta WEBER (Danish Center for particle Therapy)

9/9/23, 4:30 PM

Introduction
Radiotherapy is an effective local treatment option in patients with hepatocellular carcinoma (HCC). However, photon radiotherapy is not a widely used modality in HCC as most patients have underlying cirrhosis making the liver more sensitive to radiation induced liver disease (RILD).

The aim of this national phase II study (NCT05203120) is to investigate feasibility and safety...

33. AI-assisted proton radiography interpretation for fast detection and classification of treatment deviations’

Giuliano Perotti Bernardini

9/9/23, 4:30 PM

38. Comparison of two techniques for 4D-robust adaptive proton therapy

Suryakant Kaushik

9/9/23, 4:30 PM

27. DiffuseRT: Learning Likely Anatomical Deformations From Data

Luciano Rivetti

9/9/23, 4:30 PM

34. Dose reconstruction strategies using prompt-gamma radiation in proton therapy

Beatrice Foglia

9/9/23, 4:30 PM

INTRODUCTION
To monitor range uncertainties in proton therapy, dose reconstruction is desirable,
and it has already been proposed in the literature starting from detected secondary radiation, mostly positron emitters (PE). Prompt-gammas (PG) can be alternatively used:
emitted within nanoseconds after nuclear interactions, they can be exploited for realtime adaptation.

MATERIAL AND...

28. Dosimetric Benefit Of Online Daily Adaptive Proton Therapy For Head And Neck Cancer Patients

Evangelia Choulilitsa

9/9/23, 4:30 PM

29. Fast Proton Treatment Plan Re-Optimization Using The Reference Point Method To Account For Interfractional Anatomical Changes

Zihang Qiu

9/9/23, 4:30 PM

17. Heterogeneously hypofractionated proton therapy for Locally Advanced non-small cell lung cancer (NSCLC) - HERAN2 trial

Hanna Rahbek Mortensen (Danish Center for Particle Therapy)

9/9/23, 4:30 PM

The aim of the Danish randomized HERAN2 trial is to examine if heterogeneous and hypofractionated proton radiotherapy can improve survival compared with X-ray radiotherapy in patients with locally advanced NSCLC who are not candidates for standard chemoradiotherapy. Patients selected for proton therapy are treated at the Danish Center for Particle Therapy and hereby, we present our treatment...

24. Impact of temporal image resolution on the interplay effect in 4D Monte Carlo dose calculation for IMPT

Ivar Bengtsson (RaySearch Laboratories & KTH, Royal Institute of Technology)

9/9/23, 4:30 PM

The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with IMPT. In a conventional 4DDC, each spot is assigned to its nearest phase image in a 4DCT, based on a delivery log and a breathing signal. The doses computed on the phase images are then deformed to a reference phase and accumulated. An...

30. Integration of anatomical variations into robust plan evaluation for proton therapy

Nadine Vatterodt

9/9/23, 4:30 PM

32. Inter- and intrafractional 4D dose accumulation for evaluating ΔNTCP robustness in lung cancer

Andreas Smolders

9/9/23, 4:30 PM

36. Investigation of uncertainty maps to assess deep-learning based synthetic CT for adaptive proton therapy

Art Galapon

9/9/23, 4:30 PM

31. Joint Translation And Registration Framework: A Novel Approach To Address Misalignment In MR-Based CT Synthesis

Xia Li

9/9/23, 4:30 PM

20. Online tumor motion forecasting using Vision Transformers

Gauthier Rotsart de Hertaing (UCLouvain)

9/9/23, 4:30 PM

In radiotherapy, forecasting the motion of a lung tumor is a fundamental task for dose delivery. Indeed, anticipating the motion saves time in the decision-making process for real-time applications and could lead to a better homogeneous dose delivery and more healthy tissues spared. Our method is trained and tested on fluoroscopic sequences generated from 4D-Computed Tomography (4DCT) scans...

18. Performance of kV-CBCT imaging during megavoltage beam irradiation under phase-gated condition

Hiraku Iramina (Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University)

9/9/23, 4:30 PM

[Purpose] kV-CBCT imaging during MV beam irradiation technique has been developed on C-arm linac. The purpose of this study was to quantify the performance of the intra-irradiation imaging technique under a phase-gated condition.
[Method] TrueBeam Developer mode was used to perform the intra-irradiation imaging. Catphan504 phantom was used. To demonstrate respiratory movement, the phantom was...

21. Real-time RBE-weighted 4D-dose calculation for carbon ion therapy

Cosimo Galeone

9/9/23, 4:30 PM

Introduction
The estimation of dose errors is a key part of online adaptive particle therapy. Interplay distorts dose distributions leading to non-ideal tumor coverage and higher dose to healthy tissues.
Fast forward dose calculation (FDC) is mandatory to verify the efficacy of motion mitigation strategies during treatment. We propose and validate in silico a system to reconstruct the...

19. Spot-scanning proton therapy for breast cancer in free breathing versus deep inspiration breath-hold

Line Bjerregaard Stick (Danish Centre for Particle Therapy)

9/9/23, 4:30 PM

Background
Proton therapy for breast cancer is usually given in free breathing (FB). With the use of deep inspiration breath-hold (DIBH) technique, the location of the heart is shifted more caudally, away from the internal mammary nodes (IMN) and, thus, the dose to the heart could potentially be reduced. The aim of this study was to compare proton therapy in FB with proton therapy in DIBH for...

35. Towards automated prompt-gamma treatment verification: Feasibility of PGI simulations on cone-beam CTs

Stefanie Bertschi

9/9/23, 4:30 PM