Chia-Ying HUANG
(PSI - Paul Scherrer Institut)
05/06/2025, 11:00
Invited
Cryogenic temperatures may introduce artefacts that limit the understanding of protein dynamics, crucial to their biological functions. To address this, we developed a room-temperature (RT) X-ray crystallographic method that captures movie-like structural snapshots triggered by temperature [1]. This method revealed binding-mode changes of TL00150, a 175.15 Da fragment, in endothiapepsin....