12th International Workshop on Radiation Damage to Biological Samples

Session

Damage at New Sources - XFELs and 4th Generation Synchrotrons

DNS

3 Jun 2025, 16:00

Auditorium (Paul Scherrer Institut)

Conveners

Damage at New Sources - XFELs and 4th Generation Synchrotrons

• Nadja Zatespin

14. Investigation of radiation damage in room temperature serial macromolecular crystallography at a fourth generation Synchrotron

Samuel L. ROSE (ESRF)

03/06/2025, 17:30

Invited

Radiation damage is major concern in macromolecular crystallography (MX) where ionising X-rays used for structure determination can result in a cascade of damaging processes caused by the absorption of energy (denoted mainly as dose: absorbed energy/mass (J/kg; Gray (G)) and radiolysis of molecules. These can introduce artefacts within the structure (specific damage) and the overall data...