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Nick Hardcastle (Peter MacCallum Cancer Centre)06/11/2026, 13:00oral/poster
Objectives
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Sarcopenia is characterised by loss of skeletal muscle mass and strength, impacting physical performance and quality of life in people with cancer. In neuroendocrine tumours (NETs) it is associated with poor prognosis, but large-scale evidence quantifying its prevalence and changes with disease progression, treatment and nutritional interventions is lacking. Whole-body CTs acquired... -
Chuxin Zhang (UCLouvain)06/11/2026, 13:301oral/poster
Objective
In MR-guided adaptive radiotherapy (MRgRT) for prostate cancer, daily target re-delineation is required to account for inter-fraction anatomical changes, requiring rapid and reliable auto-segmentation. Image-quality degradation from acquisition- and patient-related factors can impair prostate MRI segmentation and may also affect uncertainty estimates. We systematically...
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Alessandra Catalano (Fondazione IRCCS Istituto Nazionale dei Tumori, Milano)06/11/2026, 14:00oral/poster
Objective
To develop an explainable artificial intelligence framework integrating radiotherapy dosimetry and quantitative imaging to identify survival-related patient phenotypes and inform personalised dose optimisation in locally advanced non-small cell lung cancer (LA-NSCLC).Methods
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This multicentre retrospective study included 388 patients treated with curative-intent... -
Ronja Stern (PSI - Paul Scherrer Institut)06/11/2026, 14:30oral/poster
Objective: Generative models can create synthetic patient cohorts for radiotherapy research, but current multimodal generators primarily sample plausible patients without explicit control over the generated anatomy (Li, 2026). This limits their use for systematic investigation of radiotherapy scenarios. We investigate a conditioned multimodal head-and-neck model that generates anatomically...
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