15–16 Sept 2011
Paul Scherrer Institut, Villigen, Switzerland
Europe/Zurich timezone

Cross-correlation based 2D structure determination from multi-particle X-ray diffraction images

16 Sept 2011, 15:30
20m
WSLA/008 (PSI)

WSLA/008

PSI

Talk XFEL Experiments in Condensed Matter XFEL Experiments in Condensed Matter

Speaker

Dr Bill Pedrini (Paul Scherrer Institut)

Description

In 1977, Kam proposed the cross-correlation method for 3D structure determination from X-ray diffraction images of multiple, identical, randomly oriented particles. The main obstacle to the practical application at the nanoscale, namely the requirement of short but intense incoming X-ray pulses, may be overcome with Free Electron Laser sources. We present the results of pilot experiments performed at a synchrotron X-ray source. The simplifications with respect to the original idea consist in the reduction of the dimensionality of the experiment from 3D to 2D, and in the "freezing" of the rotational motion of the particles to, allow sufficiently long acquisition time. We demonstrate the potential of the cross-correlation method by reconstructing the 2D structure of gold nanoparticles with size of the order of 360 nm and less.

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XFEL Experiments in Condensed Matter

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Primary author

Dr Bill Pedrini (Paul Scherrer Institut)

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