SwissFEL Photonics: "Sample Mounting and Injection Workshop"

Tuesday 20 Nov 2012, 08:15 → 17:00 Europe/Zurich

WSLA/008 (PSI)

How to deliver liquid or solid samples to the FEL X-ray beam with optimal hit rate and best possible sample economy?

The goal of the workshop is to discuss how to deliver sample material to the X-ray beam, in order to develop and/or finalize the design of the SwissFEL experimental stations. The workshop will be divided in two parts: The first part will address injection of liquid sample into the X-ray beam using a jet, as well as the transport to the beam position of solid, submicrometer sized particles by means of a gaseous or liquid medium. Of particular interest are nanocrystals of biomolecules, whereby the key consideration is „Sample economy“. It is an open question if this can be achieved by synchronizing the beam to the sample, or vice-versa. In the second part, the focus is on samples mounted on a solid support. Of special interest are 2D-crystals or 3D-nanocrystals of biomolecules, but other organic and inorganic material could be considered. The issues can be stated as „How to find and hit the sample with minimal damage of the support, and then rapidly move to the next nearby position“.

1 Introduction

Speaker: Bill Pedrini (Paul Scherrer Institut)

2 Overview

Speaker: Matthias Frank (LLNL)

3 Challenges of Sample Delivery for the European XFEL

Speaker: Joachim Schulz (E-XFEL)

Slides Challenges of Sample Delivery

10:35 Coffee break

4 Crystallography on a chip: In the quest to improve sampling efficiencies for FEL sources

Speaker: Arash Zarrine-Afsar (Univ. Toronto)

Slides Cristallography On Chip

5 Membrane sample supports for XFEL-based protein crystallography

Speaker: Dr Celestino Padeste (Paul Scherrer Institut)

Slides Membrane Supports XFEL

6 How to find Samples: precise positioning and complementary microscopy techniques

Speaker: Dr Jörg Raabe (PSI)

Slides Sample Finding Positioning

12:45 Business lunch

7 Hit rate and sample consumption for samples in liquid water

Speaker: Daniel De Ponte (CFEL)

Slides Hit Rate Sample Consumption

8 Next Generation Opportunities: From Single Particles to Simultaneous Spectroscopy / Diffraction

Speaker: Mike Bogan (SLAC)

Slides Particle Injection

14:55 Coffee break

9 Discussions

Speaker: Bill Pedrini (Paul Scherrer Institut)

10 Summary

Speaker: Dr Rafael Abela (PSI)