RAPTOR - LOOP REQUIREMENTS 4th-9th SEPTEMBER 2022

Material

122. Entrepreneurship

Mark Plesko

9/4/22, 5:30 PM

A famous physics professor once said »if you want to make money, don't go through physics. Go the direct way, study economics«. This may have been true in his time, but it certainly isn’t now. I will demonstrate with myself as example, how a “simple” physicist and a couple of physics students, like “you and me”, started on an entrepreneurial journey 20 years ago and are now running the world’s...

97. Deep Learning meets Imaging Science: Explainable Hybrid Solvers for Medical Imaging

Gitta Kutionik

9/5/22, 11:00 AM

Deep neural networks have already been tremendously successful in real-world applications, ranging from science to public life. The area of imaging sciences has been particularly impacted by deep learning-based approaches, which sometimes by far outperform classical approaches for particular problem classes. This talk shall give an introduction into this exciting research field. We will first...

98. AI in Radiotherapy – Machine Learning and Deep Learning for Treatment Planning

Zoltán Perkó

9/5/22, 12:00 PM

Over the last century radiotherapy has had a remarkable success in cancer treatment. After the early years of trial-and-error, the evidence based use of radiation has established fractionated photon treatments as standard of care for most patients. Decades of research has led to novel machinery and procedures – such as charged particle treatments, image guidance and adaptive treatments – that...

99. Big data: acquiring and using large (patient) datasets/ Big Data in a Clinical Context

Giorgio Ruffa

9/5/22, 2:30 PM

The rise and widespread adoption of internet technologies in the last twenty years have triggered the generation and storage of massive amounts of data. This abundance has fostered the development of systems able to perform distributed computations on a large scale that later came to be known as "big data technologies". As often happens in the medical technology field, digital innovations that...

100. Biostatistics

Maja Pohar Perme

9/5/22, 3:30 PM

The talk will present the basic concepts of biostatistics and statistical inference in general. We will start with the estimation of the population mean and explain the terms like sampling distribution and the standard error. We will explain why and how the central limit theorem plays a central role in the underlying statistical theory. We shall then turn to hypothesis testing and give an...

101. Inventions, patents and crime – What a researcher needs to know about IP

Matthias Schindler

9/5/22, 5:00 PM

Intellectual property (IP) helps to protect creations of the mind that include technological inventions, designs, images, symbols, slogans etc. If you create a product, publish a book, or find something new in your research, intellectual property rights ensure that you benefit from your work. These rights protect your creation or work from unfair use by others and can be a catalyst to attract...

102. Gender, Inclusion and Gendered Innovation I

Lucia Martinelli

9/5/22, 6:00 PM

Aim: to create awareness about gender issues and to stimulate practices for a good behavior.
Main Topics: (After a short presentation about myself and my involvement in science and in EPWS)
(I) State of the art of the participation of women in research with particular focus on Europe.
(II) overview about the most crucial gender issues:
-the stereotypes and the unconscious bias;
-the...

103. Control systems for ART

Jasna Hengovic

9/6/22, 8:30 AM

I will introduce our product TreatmentOne. which was developed with the future in mind, specially to support the evolution towards adaptive methodologies. It is in fact a three-in-one solution: A Record and Verify (R&V), a treatment session manager, and a treatment control system that synchronizes the operation of all devices and subsystems and enables users to perform clinical and QA...

104. Clinical QA procedures/ Clinical QA procedures and their applicability in ART

Kristin Stutzer

9/6/22, 9:30 AM

Clinical QA procedures and their applicability in APT / OAPT
Quality assurance (QA) procedures in radiotherapy are necessary to ensure an accurate and safe dose delivery to the patient. Improvement and assurance of radiotherapy safety relies on two major pillars. Incident reporting and incident learning are most meaningful for improving existing processes while prospective risk assessment,...

107. Industrialization

Caterina Brusasco

9/6/22, 11:00 AM

Placing on the market a Medical Device is subject to regulation in most of jurisdictions to ensure safety for patients and health care personnel. A new medical device needs to undergo a conformity assessment before being placed on the market and is subject to surveillance during its lifetime to ensure its safety and correct performance. According to the potential risks posed by the medical...

108. Big data: fast access, transfer, storage

Thomas Stibor

9/6/22, 12:00 PM

Data acquisition in high energy physics is a challenging task in terms of reliability and scalability. We present a framework for transferring raw acquisition data to the large-scale distributed file system Lustre and additionally archive the data in an archiving system in near real-time. The framework employs multiple queue data-structures and exploits producer-consumer paradigm to leverage...

127. Health Economics

Prof. YOLANDE LIEVENS

9/6/22, 2:00 PM

106. Logfile-based (4D) dose reconstruction

Ye Zhang

9/7/22, 8:30 AM

The interplay of motion with a highly dynamic dose delivery process like Pencil Bean Scanned (PBS) proton beam is inherently complex. Although by using four-dimensional (4D) dose calculation, the foreseen 4D dose distributions can be estimated prospectively, their accuracy to which extent can be predicted a priori is questionable, due to the large number of variables involved. Therefore,...

124. New Product Development: Systems engineering approach for Regulatory compliance

Fritz De Jongh

9/7/22, 9:30 AM

ProtonVDA was funded by the USA National Cancer Institute to develop a clinically realistic proton radiography and tomography prototype system. This funding also requires a commercialization plan, including for regulatory certification. Our research team includes several medical physicists and radiation oncologists to help ensure the clinical applicability. This talk will provide an...

112. Challenges of operating a PT facility

Karen Kirkby

9/7/22, 10:30 AM

113. Certification standards: Health, Safety, Environmental

Marjetka Kralj Kunčič

9/7/22, 2:30 PM

114. Data Constructs and Computations in Adaptive Radiotherapy

Hanne Kooy

9/7/22, 3:30 PM

Radiotherapy workflow assumed a linear sequence from intake to last treatment. Tasks were decoupled, without feedback and data was sparse. Adaptive radiotherapy (ART) presents data increase with feedback anywhere. Changes need to be processed within this changing context. Complexity management requires the use of up-to-date computing concepts.
We define two levels. The first concerns task...

105. Prompt gamma particle imaging

Christian Richter

9/7/22, 4:30 PM

The lecture will give an overview of the utilization of prompt-gamma (PG) radiation, emitted from the patient’s body during fractionated particle therapy treatment, for range and treatment verification. After the nuclear physics basics of the emission of prompt gamma rays have been refreshed, the three fundamental approaches for PG-based particle range determination will be discussed, which...

116. Clinical Monte Carlo for particles

Lars Glimelius

9/8/22, 8:30 AM

Monte Carlo is the golden standard for computing dose in radiotherapy, but has traditionally been burdened with long computation times compared to analytical dose algorithms. Due to its superior accuracy in complicated geometries, and the possibility to score additional components in addition to dose (e.g. LET), Monte Carlo can be a very useful tool for the optimization and final dose...

117. Projection Methods, Superiorization and Applications

Aviv Gibali

9/8/22, 9:30 AM

Projection methods are iterative algorithms that use projections onto sets while relying on the general principle that when a family of sets is present, then projections onto the given individual sets are easier to perform than projections onto other sets that are derived from the given individual sets.
Their robustness, low computational effort and their ability to handle huge-size problems...

109. Deformable image registration

Chiara Paganelli

9/8/22, 11:00 AM

Over the last few decades, deformable image registration (DIR) has gained popularity in image-guided adaptive radiotherapy for a number of applications, such as contour propagation, dose warping, and accumulation. The variety of proposed DIR algorithms is vast, ranging from well-known image-based iterative optimization processes to novel machine learning solutions.
However, proper...

110. (Automated) contouring in the context of ART

Jakob Sonke

9/8/22, 12:00 PM

128. Clinical needs for adaptive proton therapy

Prof. Esther Troost

9/8/22, 3:30 PM

129. Concluding remarks

9/8/22, 4:30 PM

121. Hackathon challenge

9/9/22, 8:30 AM

Coding workshop to control a Proton therapy device.

123. Public Talk: INNOVATION IN MEDICAL PHYSICS

Rock Mackie