Prof.
Raj Suryanarayanan
(College of Pharmacy, University of Minnesota)
07/05/2018, 13:25
Monday, May 7th Afternoon (Day 1 Workshop)
The disproportionation of pioglitazone hydrochloride in intact tablets was mapped by transmission-mode synchrotron X-ray diffractometry (SXRD; Argonne National Laboratories). Tablet mapping was performed in situ at the beamline using a custom-built temperature and humidity controlled setup. Presence of basic excipients (magnesium stearate or croscarmellose sodium) caused disproportionation,...
Dr
Richard Weber
(Materials Development, Inc. and Argonne National Laboratory)
07/05/2018, 13:50
Monday, May 7th Afternoon (Day 1 Workshop)
This talk will focus on the application of non-contact (containerless) methods, such as acoustic levitation, to access metastable and amorphous forms of organic compounds. The complete absence of extrinsic nucleation sites in containerless conditions enables deep supercooling and/or extreme supersaturation to be achieved for a wide variety of compositions. The ability to extend the glass...